About Prescription Opioids

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What can prescription opioids feel like?

Prescription opioids are a large group of drugs. How long the effects from these drugs last can depend on which drug you use, whether they are immediate-release or extended-release, and how you take them. Prescription opioids all have different strengths and doses and can affect everyone differently depending on their individual body. 

Remember a low dose for one person can be a high dose for another, as people’s bodies process drugs differently.

Pleasant Effects 

Unpleasant Effects 

Physical relaxation



Reduced anxiety or stress

Reduced feelings of physical pain

Feeling ‘warm’ or ‘safe’

Pleasant feeling of sleepiness

Feelings of invincibility





Feeling lethargic

Itchiness (face and body)

Lack of appetite

Mood swings


Muscle weakness


Impaired Judgement

Clumsiness or lack of coordination

Pleasant Effects 

Unpleasant Effects 

Increased relaxation

Increased euphoria

Physical sensations of ‘floating’

Lack of pain

Feeling physically numb 

Feeling emotionally numb

Increased drowsiness

Increased nausea


Excessive sweating

Changes in heartrate

Sore stomach

Slowed breathing


Increased mood swings

Mild hallucinations

Erectile dysfunction

Pleasant Effects 

Unpleasant Effects 


Severe vomiting

Severe abdominal pain

Extreme confusion and disorientation

Blue lips and cold, clammy skin
Becoming unresponsive (unable to wake up)

Losing consciousness

Severe changes in heartrate


Difficulty breathing or very shallow breathing


We spoke to a female in her 20's that uses Tramadol regularly:

“When I was first prescribed it made me feel relaxed, warm and fuzzy, but it can also make you feel a little sick. I sometimes would have trouble keeping my thoughts straight”.

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