About Synthetic Cannabinoids

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What can synthetic cannabinoids feel like?

It is important to keep in mind that there are many different types of synthetic cannabinoids, and while they share many effects, there are also lots of differences between them. Some synthetic cannabinoids like MDMB-4en-PINACA and AMB-FUBINACA are much more likely to cause serious harm or death than others.

How fast the effects come on and how long they last varies greatly depending on which type, how it is taken and how your body processes it. Many people say that the high from synthetic cannabinoids is very short lived, sometimes less than 30 minutes.

Remember, a low dose for one person can be a high dose for another as people’s bodies process drugs differently. 

Also keep in mind that, when mixed with alcohol or other drugs, synthetic cannabinoids can have different and more unpredictable effects to those listed below.

Pleasant effects

Unpleasant effects




Giggly or giddy


Socially confident

Pleasant sleepy feeling



Drowsy or groggy


Difficulty concentrating



Irritable or agitated


Mood swings

Pleasant effects

Unpleasant effects

Increased euphoria

Hallucinations (this may be a desired effect for some people)


Racing thoughts


Unpleasant hallucinations

Difficulty speaking

Difficulty moving your body

Severely dizzy or faint

Severely nauseous




Feeling panicked or having panic attacks

Fast or irregular heartbeat

Pleasant effects

Unpleasant effects


Foaming at the mouth

Chest pain

Difficulty breathing

Temporary paralysis


Intensely paranoid

Severe panic attacks



Losing consciousness (known as ‘dropping’)

A medical responder on Reddit talks about his experience of picking up a man who was high on synthetic cannabinoids:

“I was having a lot of difficulty communicating with the guy (obviously), and I couldn’t get him to focus on any of my questions.. He was also on the fastest emotional roller coaster I’ve ever seen. Crying, laughing, I’m his best friend, etc.”

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